Do not take this medicine in larger or smaller amounts or for longer than recommended. The first dose of ondansetron is usually taken before the start of your surgery, chemotherapy, or radiation treatment.
Follow your doctor's dosing instructions very carefully. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. Store at room temperature away from moisture, heat, and light. Store liquid medicine in an upright position. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose.
Do not take extra medicine to make up the missed dose. Overdose symptoms may include sudden loss of vision, severe constipation, feeling light-headed, or fainting. Ondansetron may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Get emergency medical help if you have signs of an allergic reaction: rash, hives; fever, chills, difficult breathing; swelling of your face, lips, tongue, or throat. This is not a complete list of side effects and others may occur.
Call your doctor for medical advice about side effects. Ondansetron can cause a serious heart problem, especially if you use certain medicines at the same time, including antibiotics, antidepressants, heart rhythm medicine, antipsychotic medicines, and medicines to treat cancer, malaria, HIV or AIDS. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with ondansetron.
Taking ondansetron while you are using certain other medicines can cause high levels of serotonin to build up in your body, a condition called "serotonin syndrome," which can be fatal.
Tell your doctor if you also use:. This list is not complete and many other drugs can interact with ondansetron. This includes prescription and over-the-counter medicines, vitamins, and herbal products.
Give a list of all your medicines to any healthcare provider who treats you. It is also important information to carry with you in case of emergencies. Ondansetron pronounced as on dan' se tron. Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow? What special dietary instructions should I follow? What should I do if I forget a dose?
What side effects can this medication cause? What should I know about storage and disposal of this medication? Brand names. Do not chew the film. Other uses for this medicine. What special precautions should I follow? Before taking ondansetron, tell your doctor and pharmacist if you are allergic to ondansetron, alosetron Lotronex , dolasetron Anzemet , granisetron Kytril , palonosetron Aloxi, in Akynzeo , any other medications, or any of the ingredients in ondansetron products.
Ask your pharmacist for a list of the ingredients. It is most often prescribed for cancer patients as a way to help prevent the nausea caused by chemotherapy, radiation and surgery.
It is sometimes prescribed for pregnant women dealing with morning sickness. When serotonin is released, it can initiate a vomiting reflex. Zofran is available as an oral tablet, rapidly disintegrating tablet ODT , as a liquid and occasionally given via injection. The first dose is usually taken 30 minutes before chemotherapy begins, one to two hours before radiation begins, or one hour before surgery begins.
Sometimes, patients take additional doses one-to-three times a day during chemotherapy or radiation and for one or two days after finishing treatment. Adults typically take one 8-mg tablet or rapidly disintegrating tablet or 10 mL of liquid twice a day. For patients ages 12 and older, the dosage is the same as for adults. For those ages 4 to 11, patients should take a 4-mg tablet or rapidly disintegrating tablet or 5 mL of liquid three times per day. Zofran can be taken with or without food, and patients can continue their normal diet while taking Zofran.
Emergency department use of oral ondansetron for acute gastroenteritis-related vomiting in infants and children. Phenergan Package Insert. Zofran Prescribing Information. Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. Cochrane Database of Systematic Reviews. July Impact of increasing ondansetron use on clinical outcomes in children with gastroenteritis.
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